Table 2 MIC and HC50 activities of peptides against bacterial strains and murine red blood cells (RBCs).

From: Design, characterization and structure–function analysis of novel antimicrobial peptides based on the N-terminal CATH-2 fragment

Peptides

MIC in μg/mL

GM of MIC

HC50 in μg/mL

Therapeutic index (HC50/GM of MIC)

Fold

Escherichia coli O175:H7

Salmonella typhimurium NCTC 74

Staphylococcus aureus ATCC 9155

N-15 Cath-2

64

8

 ≥ 128

19.95

97.76

2.4

10

DP1 (LLK)

16

32

16

10.2

216

10.7

4.46

DP2 (LLR)

8

32

32

10.08

145

6.7

2.8

DP3 (L3)

32

16

32

25.4

24.62

0.5

0.2

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