Figure 4 | Scientific Reports

Figure 4

From: Allogeneic MHC-matched T-cell receptor α/β-depleted bone marrow transplants in SHIV-infected, ART-suppressed Mauritian cynomolgus macaques

Figure 4The alternative text for this image may have been generated using AI.

SHIV DNA in allo-HSC transplanted MCMs. We measured copies of vDNA in (a) PBMCs and (b) peripheral lymph nodes before ART initiation, after ART but before allo-HSCTs, and post-transplant. (c) SHIV DNA levels in the tissues of MCMs B, C, and D at necropsy. Total SHIV DNA was measured by digital droplet PCR using SIV gag-specific primers and normalized to 106 cells by measuring macaque RNaseP p30, RPP30, in companion ddPCR assays. Post-transplant peripheral lymph node samples from MCM-B and MCM-D were unavailable for analysis.

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