Table 1 Characteristics of active pulmonary TB patients with and without NAA test.

From: Nucleic acid amplification tests reduce delayed diagnosis and misdiagnosis of pulmonary tuberculosis

 

No NAA

With NAA

p valuea

p valueb

p valuec

Frontline NAA

Add-on NAA

Case number

1193

282

717

   

Age

64.1 (20.0)

65.6 (19.1)

65.0 (19.1)

0.170

0.268

0.650

Male sex

826 (69.2%)

197 (69.9%)

514 (71.7%)

   

Smear test results

 < 0.001

 < 0.001

 < 0.001

Positive

222 (18.6%)

188 (66.7%)

562 (78.4%)

   

Negative

971 (81.4%)

94 (33.3%)

155 (21.6%)

   

Culture results

 < 0.001

 < 0.001

0.139

MTB

807 (67.6%)

227 (80.5%)

605 (84.4%)

   

NTM/no growth

386 (32.4%)

55 (19.5%)

102 (15.6%)

   

Interval between smear test results and NAA results, median days (IQR)

1 (0–2)

4 (2–8)

 < 0.001

Enrolled hospital

 < 0.001

 < 0.001

 < 0.001

Hospital 1

308 (25.8%)

15 (5.3%)

108 (15.1%)

   

Hospital 2

180 (15.1%)

59 (20.9%)

147 (20.5%)

   

Hospital 3

122 (10.2%)

43 (15.2%)

95 (13.2%)

   

Hospital 4

82 (6.9%)

46 (16.3%)

72 (10.0%)

   

Hospital 5

192 (16.1%)

56 (19.9%)

106 (14.8%)

   

Hospital 6

131 (11.0%)

30 (10.6%)

96 (13.4%)

   

Hospital 7

178 (14.9%)

57 (18.8%)

69 (9.6%)

   
  1. Data are presented as n (%) unless otherwise mentioned.
  2. NAA nucleic acid amplification, TB tuberculosis, MTB Mycobacterium tuberculosis.
  3. aComparison between patients with frontline NAA and no NAA test.
  4. bComparison between patients with add-on NAA and no NAA test.
  5. cComparison between patients with frontline and add-on NAA test.