Table 1 Characteristics of active pulmonary TB patients with and without NAA test.
From: Nucleic acid amplification tests reduce delayed diagnosis and misdiagnosis of pulmonary tuberculosis
No NAA | With NAA | p valuea | p valueb | p valuec | ||
|---|---|---|---|---|---|---|
Frontline NAA | Add-on NAA | |||||
Case number | 1193 | 282 | 717 | |||
Age | 64.1 (20.0) | 65.6 (19.1) | 65.0 (19.1) | 0.170 | 0.268 | 0.650 |
Male sex | 826 (69.2%) | 197 (69.9%) | 514 (71.7%) | |||
Smear test results | < 0.001 | < 0.001 | < 0.001 | |||
Positive | 222 (18.6%) | 188 (66.7%) | 562 (78.4%) | |||
Negative | 971 (81.4%) | 94 (33.3%) | 155 (21.6%) | |||
Culture results | < 0.001 | < 0.001 | 0.139 | |||
MTB | 807 (67.6%) | 227 (80.5%) | 605 (84.4%) | |||
NTM/no growth | 386 (32.4%) | 55 (19.5%) | 102 (15.6%) | |||
Interval between smear test results and NAA results, median days (IQR) | – | 1 (0–2) | 4 (2–8) | – | – | < 0.001 |
Enrolled hospital | < 0.001 | < 0.001 | < 0.001 | |||
Hospital 1 | 308 (25.8%) | 15 (5.3%) | 108 (15.1%) | |||
Hospital 2 | 180 (15.1%) | 59 (20.9%) | 147 (20.5%) | |||
Hospital 3 | 122 (10.2%) | 43 (15.2%) | 95 (13.2%) | |||
Hospital 4 | 82 (6.9%) | 46 (16.3%) | 72 (10.0%) | |||
Hospital 5 | 192 (16.1%) | 56 (19.9%) | 106 (14.8%) | |||
Hospital 6 | 131 (11.0%) | 30 (10.6%) | 96 (13.4%) | |||
Hospital 7 | 178 (14.9%) | 57 (18.8%) | 69 (9.6%) | |||