Table 2 Cox proportional-hazards regression models for overall survival, prostate cancer-specific mortality and biochemical recurrence (model 1), adjusted by propensity scores (model 2), and Gleason score (model 3).

From: Mortality and biochemical recurrence after surgery, brachytherapy, or external radiotherapy for localized prostate cancer: a 10-year follow-up cohort study

 

Model 1

Model 2

Model 3

HR (95% CI)

p-value

HR (95% CI)

p-value

HR (95% CI)

p-value

Overall Survival

Radical prostatectomy

Ref

 

Ref

 

Ref

 

Brachytherapy

1.67

(1.10—2.52)

0.015

1.32

(0.75 – 2.33)

0.342

1.36

(0.77—2.42)

0.292

External radiotherapy

1.98

(1.28—3.06)

0.002

1.40

(0.78—2.51)

0.259

1.44

(0.80—2.59)

0.222

Propensity scorea

      

Propensity scoreb

  

1.50

(0.64 – 3.52)

0.347

1.44

(0.57—3.61)

0.442

Gleason score

  

2.36

(0.96 – 5.78)

0.061

2.33

(0.95—5.74)

0.066

 ≤ 6

    

Ref

 

7

    

0.96

(0.60—1.55)

0.882

Prostate Cancer-Specific Mortalitya

Radical prostatectomy

Ref

 

Ref

 

Ref

 

Brachytherapy

5.55

(0.71—43.24)

0.100

4.45

(0.69 – 28.71)

0.120

4.41

(0.69—28.29)

0.120

External radiotherapy

12.23

(1.61—92.95)

0.016

9.46

(1.55 – 57.79)

0.015

9.37

(1.53—57.21)

0.015

Propensity scorea

  

1.54

(0.15 – 16.05)

0.720

1.58

(0.17—14.45)

0.690

Propensity scoreb

  

1.85

(0.26 – 12.98)

0.540

1.85

(0.27—12.52)

0.530

Gleason score

      

 ≤ 6

    

Ref

 

7

    

1.04

(0.31—3.47)

0.960

Biochemical recurrencea

Radical prostatectomy

Ref

 

Ref

 

Ref

 

Brachytherapy

1.14

(0.78—1.67)

0.490

1.89

(1.20 – 2.95)

0.006

1.93

(1.23—3.03)

0.004

External radiotherapy

1.76

(1.20—2.59)

0.004

2.50

(1.60 – 3.89)

 < 0.001

2.56

(1.64—3.98)

 < 0.001

Propensity scorea

  

0.34

(0.17 – 0.67)

0.002

0.36

(0.17—0.75)

0.006

Propensity scoreb

  

0.52

(0.26 – 1.05)

0.067

0.52

(0.26—1.06)

0.074

Gleason score

      

 ≤ 6

    

Ref

 

7

    

1.05

(0.86—1.29)

0.610

  1. 95% CI 95% Confidence Interval, HR Hazard Ratio, Propensity Scorea adjustment in brachytherapy with the entire cohort, Propensity Scoreb adjustment in external radiotherapy with the entire cohort.
  2. aAdjusted by competing risk.