Table 1 Baseline patient and tumor characteristics (n = 431).

From: Improved overall survival is associated with adjuvant chemotherapy after definitive concurrent chemoradiotherapy for N3 nasopharyngeal cancer

Characteristics

Adjuvant PF Chemotherapy

(n = 152)

Observation

(n = 279)

p value

Sex

  

0.26

Male

127 (83.6)

219 (78.5)

 

Female

25 (16.4)

60 (21.5)

 

Age, median (IQR)

46 (38.8–53)

50 (41–58)

0.001

Age, mean (SD)

45.8 (10.8)

49.6 (12.7)

0.002

Histology

  

0.04

Lymphoepithelial / undifferentiated / NOS carcinoma

38 (25.0)

42 (15.1)

 

Squamous cell carcinoma, keratinizing or NOS

3 (2.0)

7 (2.5)

 

Squamous cell carcinoma, non-keratinizing

111 (73.0)

230 (82.4)

 

Clinical T classification

  

0.81

T1

51 (33.6)

106 (38.0)

 

T2

30 (19.7)

51 (18.3)

 

T3

34 (22.4)

55 (19.7)

 

T4

37 (24.3)

67 (24.0)

 

Clinical N classification

  

0.24

N3a

42 (27.6)

94 (33.7)

 

N3b

110 (72.4)

185 (66.3)

 

Radiotherapy dose (Gray), median (IQR)

70 (70–72)

72 (70–72)

0.23

Radiotherapy fractions, median (IQR)

35 (35–37)

36 (35–37)

0.83

Median (IQR) follow-up, years

4.7 (3.7–6.6)

4.0 (2.6–6.6)

0.11

  1. IQR, interquartile range; SD, standard deviation; NOS, not otherwise specified.