Table 2 Univariable and multivariable Cox proportional hazards model for overall survival (n = 431).
Variable | Univariable | Multivariable | ||
|---|---|---|---|---|
Hazard ratio (95% CI) | p value | Hazard ratio (95% CI) | p value | |
Age, continuous | 1.03 (1.01–1.04) | < 0.001 | 1.02 (1.01–1.04) | < 0.001 |
Sex | ||||
Male | Reference | Reference | ||
Female | 0.81 (0.55–1.20) | 0.30 | 0.78 (0.53–1.16) | 0.22 |
Histology | ||||
Lymphoepithelial / undifferentiated / NOS carcinoma | 0.78 (0.53–1.15) | 0.21 | 0.94 (0.63–1.39) | 0.74 |
Squamous cell carcinoma, keratinizing or NOS | 0.87 (0.32–2.34) | 0.78 | 0.84 (0.31–2.28) | 0.73 |
Squamous cell carcinoma, non-keratinizing | Reference | Reference | ||
Clinical T classification | ||||
T1 | Reference | Reference | ||
T2 | 1.52 (0.98–2.37) | 0.06 | 1.61 (1.04–2.50) | 0.03 |
T3 | 1.63 (1.07–2.48) | 0.02 | 1.72 (1.13–2.62) | 0.01 |
T4 | 1.99 (1.36–2.93) | < 0.001 | 2.18 (1.48–3.22) | < 0.001 |
Clinical N classification | ||||
N3a | Reference | Reference | ||
N3b | 1.63 (1.16–2.29) | 0.004 | 1.61 (1.14–2.28) | 0.007 |
Adjuvant treatment | ||||
Observation | Reference | Reference | ||
Adjuvant PF chemotherapy | 0.61 (0.43–0.84) | 0.003 | 0.61 (0.43–0.86) | 0.005 |
