Table 1 Baseline physiologic data for the experimental groups.

From: Spontaneous breathing promotes lung injury in an experimental model of alveolar collapse

Variable

SB

Early MV

Late MV

p value

Median (IQR)

Median (IQR)

Median (IQR)

Weight (kg)

32 (29–36)

36 (27–36)

30 (26–33)

0.541

HR (bpm)

77 (55–89)

72 (66–84)

62 (45–93)

0.948

MAP (mmHg)

84 (73–90)

90 (83–92)

91 (80–101)

0.300

CO (l/min)

2.7 (2.5–3.8)

3.7 (3.2–4.3)

3.4 (3.0–3.8)

0.222

EVLW (ml)

351 (276–404)

318 (261–351)

322 (285–571)

0.383

ITBV (ml)

637 (590–722)

722 (611–850)

752 (698–849)

0.216

GEDV (ml)

510 (472–579)

569 (490–681)

639 (560–761)

0.137

Crs (ml/cmH2O)

30 (24–38)

28 (18–32)

34 (28–38)

0.321

PaO2/FIO2

442 (423–513)

441 (367–464)

371 (304–431)

0.071

PaCO2, mmHg

43.5 (27–68)

39.6 (31–51)

43.8 (39–72)

0.172

pH

7.4 (7.2–7.5)

7.5 (7.4–7.6)

7.3 (7.1–7.4)

0.055

  1. MV: mechanical ventilation, SB: spontaneous breathing, HR: heart rate, MAP: mean arterial pressure, CO: cardiac output, EVLW: extravascular lung water, ITBV: intrathoracic blood volume, GEDV: global end diastolic volume, Crs: respiratory system compliance.