Figure 1 | Scientific Reports

Figure 1

From: Sirtuin 5 levels are limiting in preserving cardiac function and suppressing fibrosis in response to pressure overload

Figure 1

SIRT5OE mice exhibit decreased mildly decreased cardiac lysine malonylation. (A) Immunoblot analysis of SIRT5 expression in heart samples presented in c-e. Original immunoblot images are presented in Supplemental Fig. 7A. (B) Weight (g) of WT and SIRT5OE male and female mice with age. (C-E) Representative immunoblot analysis of succinyl-lysine (Ksucc), and malonyl-lysine (Kmal) levels in WT and SIRTOE hearts, with quantification. Original immunoblot images are presented in Supplemental Fig. 7B-C.

Back to article page