Figure 6
Reduced overall inflammation in SP-treated pressure injury. (a) Profiler screening of a panel of cytokines/chemokines in tissue extract from pressure injury at d7 post-initiation of I/R. Data displaying relative expression and expressed as mean pixel intensity, mean of n = 2 per time point per group. Total inflammatory cell infiltrate representative H&E stained tissue section images (b) and quantification (c) in mouse pressure injury. Scale bar = 100 µm. (d) Quantification of nitrite in pressure injury tissue extracts at d7. Data in (c, d) presented as a box and whisker plot and presented as total immune cells per unit area as a percentage of the unwounded vehicle-treated control (c) or µmol/L/mg total cell protein (d). Data were analyzed by two-way ANOVA with Bonferonni post-hoc test.
