Table 1 Baseline characteristics of patients with and without SCA.
SCA | p-value | ||
|---|---|---|---|
No | Yes | ||
4,040,071 | 16,352 | ||
Male | 2,221,898 (55.0%) | 11,633 (71.1%) | < 0.001 |
Age (years) | 47.0 ± 14.1 | 62.0 ± 13.2 | < 0.001 |
Age group | |||
20–29 | 501,371 (12.4%) | 245 (1.5%) | < 0.001 |
30–39 | 778,093 (19.3%) | 717 (4.4%) | |
40–49 | 1,063,833 (26.3%) | 2026 (12.4%) | |
50–59 | 857,767 (21.2%) | 3181 (19.5%) | |
60–69 | 543,973 (13.5%) | 4515 (27.6%) | |
70–79 | 257,092 (6.4%) | 4591 (28.1%) | |
80 | 37,942 (0.9%) | 1077 (6.6%) | |
Body mass index (kg/m2) | 23.7 ± 3.2 | 23.8 ± 3.4 | 0.138 |
Waist circumference (cm) | 80.2 ± 9.5 | 83.5 ± 8.9 | < 0.001 |
Smoking | |||
Never-smoker | 2,399,679 (59.4%) | 7916 (48.4%) | < 0.001 |
Ex-smoker | 581,485 (14.4%) | 3128 (19.1%) | |
Current-smoker | 1,058,907 (26.2%) | 5308 (32.5%) | |
Alcohol consumption | |||
Non-drinker | 2,077,053 (51.4%) | 9534 (58.3%) | < 0.001 |
Mild-drinker | 1,641,427 (40.6%) | 5263 (32.2%) | |
Heavy-drinker | 321,591 (8.0%) | 1555 (9.5%) | |
Regular exercise | 733,609 (18.2%) | 3148 (19.3%) | < 0.001 |
Income (lowest 20%) | 704,587 (17.4%) | 3075 (18.8%) | < 0.001 |
Diabetes mellitus | 349,134 (8.6%) | 4264 (26.1%) | < 0.001 |
Diabetes mellitus stage | |||
Non-diabetic | 2,776,161 (68.72%) | 7970 (48.7%) | < 0.001 |
Impaired fasting glucose | 914,776 (22.64%) | 4118 (25.2%) | |
New onset diabetes | 119,558 (2.96%) | 1025 (6.3%) | |
Diabetic < 5 years | 118,215 (2.93%) | 1272 (7.8%) | |
Diabetic ≥ 5 years | 111,361 (2.76%) | 1967 (12.0%) | |
Glucose (mg/dL) | 97.2 ± 23.8 | 110.0 ± 41.5 | < 0.001 |
Hypertension | 1,082,382 (26.8%) | 9331 (57.1%) | < 0.001 |
Hypertension stage | |||
Non-hypertensive | 1,383,411 (34.24%) | 2566 (15.7%) | < 0.001 |
Pre-hypertension | 1,574,278 (38.97%) | 4455 (27.2%) | |
Hypertension | 334,302 (8.27%) | 1777 (10.9%) | |
Hypertension with medication | 748,080 (18.52%) | 7554 (46.2%) | |
Systolic blood pressure (mmHg) | 122.4 ± 15.0 | 129.3 ± 17.2 | < 0.001 |
Diastolic blood pressure (mmHg) | 76.3 ± 10.0 | 78.9 ± 11.0 | < 0.001 |
Dyslipidemia | 732,983 (18.1%) | 4610 (28.2%) | < 0.001 |
Dyslipidemia stage | |||
Total cholesterol < 240 (mg/dL) | 3,307,088 (81.9%) | 11,742 (71.8%) | < 0.001 |
Total cholesterol ≥ 240 | 347,131 (8.6%) | 1541 (9.4%) | |
Total cholesterol ≥ 240 with medication | 385,852 (9.6%) | 3069 (18.8%) | |
Cholesterol (mg/dL) | 195.3 ± 41.1 | 195.1 ± 44.3 | 0.549 |
High-density lipoprotein (mg/dL) | 56.5 ± 32.9 | 53.6 ± 30.9 | < 0.001 |
Low-density lipoprotein (mg/dL) | 121.2 ± 214.2 | 115.0 ± 97.8 | < 0.001 |
Chronic kidney disease | 275,854 (6.8%) | 2740 (16.8%) | < 0.001 |
eGFR (mL/min/1.73m2) | 87.6 ± 44.9 | 80.4 ± 34.7 | < 0.001 |
