Table 3 Multivariable analysis of length of time of PROM and neonatal outcomes: Adjusted OR of other factors at time thresholds with significant differences of early-onset pneumonia in 7 days according to length of time of PROM.

From: Latency period of PROM at term and the risk of neonatal infectious diseases

Time threshold of PROM(h)a

Number of neonates

Rates of early onset pneumonia in 7 days

Early-onset pneumonia in 7 days, OR [95% CI]

P value

Power

≥ 10

4882

1.78%

1.291 [0.803, 2.076]

0.2915

0.2309

≥ 12

4328

1.78%

1.256 [0.799, 1.974]

0.3240

0.2225

≥ 14

3833

1.91%

1.532 [0.981, 2.391]

0.0606

0.6547

≥ 16

3388

1.98%

1.704 [1.104, 2.628]

0.0160

0.8578

≥ 18

2986

1.98%

1.683 [1.103, 2.570]

0.0159

0.8468

≥ 20

2634

2.05%

1.747 [1.149, 2.657]

0.0090

0.8858

≥ 22

2309

2.04%

1.613 [1.061, 2.450]

0.0252

0.7543

  1. Controlling for the city where the hospital locates, the mother’s age, education level, chorioamnionitis, induction of labor, prenatal antibiotic treatment, mode of delivery, amniotic fluid pollution, neonate’s sex, Apgar Score.
  2. aLength of time of PROM from 0 h through specific time threshold.
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