Figure 2 | Scientific Reports

Figure 2

From: Maternal stress induced endoplasmic reticulum stress and impaired pancreatic islets’ insulin secretion via glucocorticoid receptor upregulation in adult male rat offspring

Figure 2

Effect of perinatal stress on plasma glucose level (A) and AUC (B), plasma insulin level (C) and AUC (D) during OGTT in young adult male offspring. Each point and column represent mean ± SEM (n = 6 rats/group, 6 litters/group); Data was analyzed using two-way repeated measures ANOVA followed by Tukey’s post hoc test; *P < 0.05, **P < 0.01, ***P < 0.001 versus CTRL group; $$P < 0.01 versus PS group; οοP < 0.01, οοοP < 0.001 versus LS group; φφP < 0.01 versus PPPS group; ɛɛɛP < 0.001 versus PLS group. CTRL non stress, PPPLS pre-pregnancy, pregnancy, lactation stress, PPS pre-pregnancy stress, PS pregnancy stress, LS lactation stress, PPPS pre-pregnancy, pregnancy stress, PLS pregnancy, lactation stress, PPLS pre-pregnancy, lactation stress.

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