Figure 1
From: Thalamic volumetric abnormalities in type 1 diabetes mellitus and ‘peripheral’ neuropathy
Examples of thalamic segmentation on bias corrected inversion recovery (IR) turbo spin echo (TSE) T1-weighted images (T1-WI) from one patient with nonpainful diabetic peripheral neuropathy (DPN) in the top row and one patient with painful DPN in the middle row. In the bottom row, an example of a similar segmentation procedure on a 46-year-old healthy subject is shown. This example is presented for visualization purposes only, and was randomly selected from a sample of a previous study using similar IR TSE T1-WI to segment deep gray matter structures11. Please note the apparent reduction of thalamic volume (especially the thinner cross-sectional thalamic distance) in the patient with nonpainful DPN, especially in the right thalamus, relative to the other examples.
