Table 1 Basline characteristics of the patients (N = 1048).

From: A retrospective observational study of serum uric acid and in-hospital mortality in acute type A aortic dissection

Characteristic

Uric acid (umol/L) (Tertile)

p value

T1 (8.38–283.90)

T2 (284.60–389.30)

T3 (389.50–986.40)

No. of patients

349

349

350

 

Age (years, mean ± sd)

51.26 ± 11.90

50.11 ± 11.21

49.15 ± 11.22

0.052

Gender (female)

138 (39.54%)

73 (20.92%)

43 (12.29%)

 < 0.001

BMI (Kg/m2, mean ± sd)

23.85 ± 4.11

25.24 ± 4.66

25.95 ± 4.55

 < 0.001

Smoking

85 (24.36%)

92 (26.36%)

99 (28.29%)

0.499

Hypertension

234 (67.05%)

244 (69.91%)

248 (70.86%)

0.524

Diabetes

9 (2.58%)

8 (2.29%)

9 (2.57%)

0.962

Marfan syndrome

8 (2.29%)

15 (4.30%)

8 (2.29%)

0.195

Bicuspid aortic valve

5 (1.43%)

4 (1.15%)

2 (0.57%)

0.523

CRI

9 (2.58%)

2 (0.57%)

13 (3.71%)

0.019

Stroke

11 (3.15%)

13 (3.72%)

13 (3.71%)

0.896

Atherosclerosis

23 (6.59%)

18 (5.16%)

18 (5.14%)

0.635

Time to presentation (h, median (Q1–Q3))

36.00 (15.00–120.00)

24.00 (10.00–72.00)

18.00 (10.00–48.00)

0.777

SBP (mmHg, mean ± sd)

139.79 ± 28.37

139.98 ± 30.65

140.14 ± 33.05

0.988

DBP (mmHg, mean ± sd)

75.29 ± 18.33

75.77 ± 18.29

76.80 ± 20.07

0.557

Aortic diameter (mm)

44.55 ± 10.97

44.68 ± 10.48

44.10 ± 10.08

0.743

Aortic regurgitation

167 (47.85%)

155 (44.41%)

175 (50.00%)

0.329

Abdominal vessel involvement

131 (37.54%)

122 (34.96%)

128 (36.57%)

0.774

Arch vessel involvement

118 (33.81%)

111 (31.81%)

131 (37.43%)

0.284

EF value (%)

65.24 ± 7.01

64.82 ± 8.02

63.71 ± 9.26

0.037

Cr (umol/L median(Q1–Q3))

71.30 (54.10–86.30)

80.30 (65.50–110.00)

117.45 (83.23–164.88)

 < 0.001

BUN (mmol/L median(Q1–Q3))

6.10 (4.54–8.27)

6.93 (5.39–9.06)

8.70 (6.36–13.06)

 < 0.001

eGFR

94.30(72.37–124.04)

91.35(65.03–120.81)

65.51(42.56–103.19)

 < 0.001

TG (mmol/L)

1.45 ± 0.86

1.54 ± 1.16

1.69 ± 1.35

0.019

TC (mmol/L)

3.89 ± 0.99

3.97 ± 0.94

4.00 ± 0.94

0.284

HDL (mmol/L)

1.45 ± 4.61

1.14 ± 0.31

1.33 ± 4.47

0.534

LDL (mmol/L)

2.02 ± 1.78

2.13 ± 0.85

2.24 ± 0.86

0.058

D-dimer (ug/mL)

4.00 (2.30–9.00)

3.79 (2.25–9.50)

4.53 (2.74–15.93)

0.019

FDP (ug/mL)

15.60 (7.60–35.30)

17.94 (7.49–51.29)

30.50 (11.65–67.58)

 < 0.001

CRP (mg/L)

62.10 (13.10–116.00)

41.50 (9.72–108.00)

30.75 (8.23–89.38)

0.012

Operation

244 (69.91%)

232 (66.48%)

207 (59.14%)

0.009

Symptom

   

0.948

 Chest pain

253 (72.49%)

248 (71.06%)

250 (71.43%)

 

 Back pain

45 (12.89%)

47 (13.47%)

44 (12.57%)

 

 Abdominal pain

12 (3.44%)

13 (3.72%)

13 (3.71%)

 

 Syncope

11 (3.15%)

18 (5.16%)

12 (3.43%)

 

 others

28 (8.03%)

23 (6.59%)

31(8.85%)

 

Coronary malperfusion

8 (2.29%)

11 (3.15%)

40 (11.43%)

 < 0.001

Mesenteric malperfusion

5 (1.43%)

4 (1.15%)

6 (1.71%)

0.819

Cerebral malperfusion

11 (3.15%)

18 (5.16%)

12 (3.43%)

0.334

Hypotension/shock

8 (2.29%)

16 (4.58%)

20 (5.71%)

0.071

Cardiac tamponade

2 (0.57%)

4 (1.15%)

8 (2.29%)

0.133

Mortality

   

 < 0.001

 Survivor

267 (76.50%)

238 (68.19%)

205 (58.57%)

 

 Non-survivor

82 (23.50%)

111 (31.81%)

145 (41.43%)

 
  1. BMI body mass index, SBP systolic blood pressure, DBP diastole blood pressure, Cr creatinine, BUN blood urea nitrogen, eGFR estimated glomerular filtration rate, TG triglyceride, TC total cholesterol, HDL high-density lipoprotein, LDL low-density lipoprotein, FDP fibrinogen and fibrin degradation products, CRP C-reactive protein, CRI chronic renal insufficiency, EF ejection fraction.