Table 5 The effect of ruscogenin, liquiritin, hesperetin on A549 cells (values represented as mean ± SD. ##P < 0.01 versus control group. **P < 0.01, *P < 0.05, versus model group).
Groups | Concentrations/(mg/ml) | E-cad/(ng/ml) | α-SMA/(ng/ml) | FN/(ng/ml) |
|---|---|---|---|---|
Control | 0.0 | 7215.4 | 0.21 | 164,832.3 |
Model | 0.0 | 2578.3## | 15.84## | 341,945.2## |
Ruscogenin | 2.5 | 2643.9 | 16.19 | 341,306.5 |
5.0 | 3893.4 | 12.71 | 326,684.1 | |
10.0 | 4195.4 | 8.38** | 303,773.8 | |
20.0 | 4051.3 | 6.58** | 281,629.9 | |
Liquiritin | 1.0 | 3439.3 | 16.46 | 345,307.5 |
2.0 | 3833.7 | 13.82 | 319,617.8 | |
3.0 | 3724.3 | 12.48 | 317,404.5 | |
4.0 | 4277.7 | 11.18 | 294,040.3 | |
5.0 | 4152.2 | 8.78* | 281,506.8 | |
Hesperetin | 4.0 | 3610.8 | 12.34 | 359,093.6 |
8.0 | 4148.4 | 12.79 | 323,710.7 | |
16.0 | 4028.9 | 8.09** | 316,028.8 | |
32.0 | 4367.9 | 6.53** | 307,689.5 |
