Table 1 Baseline characteristics for the Clinical-Consecutive cohort.
Characteristic | All | Normal QRS-T angle | Increased QRS-T angle | p value |
|---|---|---|---|---|
Number, n (%) | 783 (100) | 377 (48) | 406 (52) | n/a |
Age, y | 55 (43 to 64) | 53 (38 to 62) | 57 (46 to 65) | < 0.001 |
Female sex, % | 342 (44) | 149 (40) | 193 (48) | 0.02 |
LVH | 227 (29) | 59 (18) | 168 (41) | < 0.001 |
ECV, % | 27.6 (25.3 to 30.3) | 26.8 (24.8 to 29.1) | 28.5 (25.7 to 31.1) | < 0.001 |
EDVI, mL/m2 | 78.3 (66.1 to 97.3) | 74.5 (63.7 to 89.3) | 84.5 (67.6 to 111.2) | < 0.001 |
GLS, % | − 16.2 (− 18.8 to − 12.3) | − 17.6 (− 19.5 to − 15.3) | − 13.9 (− 17.3 to − 9.8) | < 0.001 |
LVEF, % | 58.5 (47.0 to 65.0) | 61.0 (55.3 to 66.0) | 55.0 (34.3 to 63.0) | < 0.001 |
LVMI, g/m2 | 55.3 (44.9 to 67.1) | 51.7 (43.6 to 61.4) | 59.4 (46.8 to 73.8) | < 0.001 |
BMI, kg/m2 | 28.6 (24.4 to 33.9) | 28.3 (24.4 to 33.5) | 29.0 (24.4 to 34.0) | 0.41 |
BSA, m2 | 2.0 (1.8 to 2.2) | 2.0 (1.8 to 2.2) | 2.0 (1.8 to 2.2) | 0.28 |
Infarct, n (%) | 165 (21) | 43 (11) | 122 (30) | < 0.001 |
Infarct size*, % | 14.7 (5.9 to 22.3) | 8.8 (4.4 to 17.5) | 15.8 (7.7 to 24.1) | < 0.001 |
Non-ischemic scar, n (%) | 137 (17) | 50 (13) | 87 (21) | 0.003 |
Non-ischemic scar size*, % | 2.9 (1.5 to 5.7) | 2.6 (0.7 to 6.1) | 2.9 (1.5 to 5.1) | 0.50 |
Conventional ECG-LVH criteria | ||||
Sokolow-Lyon index, mV | 1.8 (1.4 to 2.3) | 1.7 (1.4 to 2.2) | 1.9 (1.4 to 2.1) | 0.39 |
Cornell voltage, mV | 1.4 (1.0 to 1.8) | 1.2 (0.95 to 1.6) | 1.6 (1.2 to 2.1) | < 0.001 |
Cornell product, mV*ms | 132 (94 to 176) | 114 (82 to 150) | 152 (110 to 206) | < 0.001 |
QRS duration, ms | 90 (84 to 98) | 88 (82 to 96) | 92 (84 to 100) | 0.03 |
Comorbidity, n, (%) | ||||
Hypertension | 398 (51) | 158 (42) | 240 (52) | < 0.001 |
Diabetes mellitus | 171 (22) | 57 (15) | 114 (25) | < 0.001 |
Smoking status, n, (%) | ||||
Current smoker | 129 (16) | 47 (12) | 82 (18) | 0.004 |
Ex-smoker | 246 (31) | 112 (30) | 134 (29) | 0.32 |
Medication, n, (%) | ||||
ACEi/ARB | 315 (40) | 114 (30) | 201 (44) | < 0.001 |
Aspirin or other antiplatelets | 397 (51) | 157 (42) | 240 (52) | < 0.001 |
Beta-blockers | 387 (49) | 143 (38) | 244 (53) | < 0.001 |
Digoxin | 23 (3) | 4 (1) | 19 (5) | 0.01 |
Insulin | 121 (15) | 40 (11) | 81 (17) | < 0.001 |
Loop diuretics | 164 (21) | 45 (12) | 119 (26) | < 0.001 |
Oral hypoglycemics | 54 (7) | 12 (3) | 42 (9) | < 0.001 |
Statins | 315 (40) | 124 (33) | 191 (42) | < 0.001 |
General indication for CMR: known or suspected disease, n (%) | ||||
Arrhythmia or syncope | 147 (19) | 59 (16) | 88 (22) | 0.03 |
Coronary artery disease/vasodilator stress test | 365 (47) | 230 (61) | 135 (33) | < 0.001 |
Dyspnea | 56 (7) | 38 (10) | 18 (4) | 0.002 |
Non-ischemic cardiomyopathy | 181 (23) | 114 (38) | 67 (17) | < 0.001 |
Pre-operation evaluation | 37 (5) | 21 (6) | 16 (4) | 0.28 |
Valvular disease | 48 (6) | 24 (6) | 24 (6) | 0.79 |