Table 2 Univariate and Multivariate Cox Regression Analysis of the Associations between Clinicopathological Features and OS in Patients with Metastatic CDC.

From: Impact of treatment modalities on prognosis of patients with metastatic renal collecting duct carcinoma

Characteristics

Univariable analysis

Multivariable analysis

HR (95% CI)

P

HR (95% CI)

P

Age(years)

    

 < 68

Reference

 

Reference

 

 ≥ 68

1.67 (1.06–2.65)

0.028

1.35 (0.83–2.20)

0.219

Sex

    

Female

Reference

   

Male

1.11 (0.81–1.52)

0.530

  

Race

    

Black

Reference

   

White

1.05 (0.63–1.77)

0.841

  

Other*

0.62 (0.25–1.55)

0.307

  

Laterality

    

Left

Reference

   

Right

1.13 (0.73–1.73)

0.586

  

Tumor size(cm)

    

 < 7

Reference

   

 ≥ 7

1.38 (0.90–2.13)

0.144

  

Pathological grade

    

Grade II

Reference

   

Grade III

1.24 (0.48–3.18)

0.660

  

Grade IV

0.63 (0.23–1.76)

0.378

  

T stage

    

T1

Reference

   

T2

1.47 (0.49–4.46)

0.493

  

T3

0.91 (0.51–1.61)

0.743

  

T4

1.13 (0.54–2.34)

0.745

  

N stage

    

N0

Reference

   

N1

1.01 (0.60–1.70)

0.965

  

N2

0.77 (0.44–1.33)

0.343

  

Surgery

    

Yes

Reference

 

Reference

 

No

2.02 (1.26–3.23)

0.004

2.33 (1.45–3.77)

 < 0.001

Radiotherapy

    

Yes

Reference

   

No/Unknown

1.05 (0.63–1.74)

0.862

  

Chemotherapy

    

Yes

Reference

 

Reference

 

No/Unknown

2.79 (1.76–4.42)

 < 0.001

2.79 (1.73–4.48)

 < 0.001

  1. CDC, renal collecting duct carcinoma; CI, confidence interval; HR, hazard ratio; OS, overall survival.
  2. *Other included American Indian/Alaskan Native and Asian/Pacific Islander.
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