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Figure 1

From: Altered resting-state functional connectivity within corticostriatal and subcortical-striatal circuits in chronic pain

Figure 1

NAcc-MPFC functional connectivity in patients with fibromyalgia vs. healthy controls. (A) Location of the right NAcc ROI (top) and bilateral MPFC VOI (bottom). (B) Right NAcc ROI (top)—Bilateral MPFC VOI (bottom). (C) NAcc-MPFC connectivity in patients with fibromyalgia vs. healthy controls. Effect size refers the average difference in Fisher-transformed correlation coefficients. Error bars indicate the 95% confidence interval. (D) Correlations between NAcc-MPFC connectivity and STAI-Trait within the fibromyalgia group. ROI, region of interest, i.e., brain region defined; VOI, volume of interest, i.e., sphere at specific coordinates; NAcc, nucleus accumbens; MPFC, medial prefrontal cortex.

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