Table 1 Summary of changes in the 3 animal models of MS.
From: Expression of antioxidant enzymes in lesions of multiple sclerosis and its models
| Â | POVPC | LPC | EAE |
|---|---|---|---|
CD68 | Upregulated | Upregulated | Upregulated |
OLIG2 | Upregulated | Upregulated | No change |
GFAP | Downregulated | Downregulated | No change |
SOD1 | Upregulated | Upregulated | Upregulated |
CD68+ SOD1+ | Upregulated | Upregulated | Upregulated |
GFAP+ SOD1+ | No change | Upregulated | Downregulated |
HO-1 | Upregulated | Upregulated | No change |
CD68+ HO-1+ | Upregulated | No change | Upregulated |
GFAP+ HO-1+ | No change | No change | No change |
PRDX5 | Upregulated | Upregulated | Upregulated |
CD68+ PRDX5+ | Upregulated | Upregulated | Upregulated |
GFAP+ PRDX5+ | No change | Upregulated | Upregulated |
GPX4 | Upregulated | Upregulated | Upregulated |
CD68+ GPX4+ | Upregulated | Upregulated | Upregulated |
OLIG2+ GPX4+ | Downregulated | Downregulated | Upregulated |
