Table 1 Demographic data according to the era: antigenemia and PCR.

From: Transition from antigenemia to quantitative nucleic acid amplification testing in cytomegalovirus-seropositive kidney transplant recipients receiving preemptive therapy for cytomegalovirus infection

Results

Total

(N = 363)

Antigenemia era

(N = 177)

PCR era

(N = 186)

P-value

Recipient age, years

49.0 (37.0; 57.0)

50.0 (39.2; 57.0)

50.0 (41.0; 60.0)

0.38

Recipient sex, male, N (%)

199 (54.8)

92 (52.0)

107 (57.5)

0.29

Recipient ethnicity, N (%)

   

0.007

White

199 (54.8)

83 (46.9)

116 (62.4)

 

Pardo

177 (32.3)

71 (40.1)

46 (24.7)

 

Afro Brazilian

40 (11.0)

21 (11.9)

19 (10.2)

 

Other

7 (1.9)

2 (1.1)

5 (2.7)

 

Cause of CKD, N (%)

   

0.22

Unknown

162 (44.6)

80 (45.2)

82 (44.1)

 

Diabetes mellitus

52 (14.3)

22 (12.4)

30 (16.1)

 

Glomerulonephritis

47 (12.9)

18 (10.2)

29 (15.6)

 

Hypertension

29 (8.0)

18 (10.2)

11 (5.9)

 

ADPKD

23 (6.3)

10 (5.6)

13 (7.0)

 

Other

50 (13.8)

29 (16.4)

21 (11.3)

 

Time on dialysis, months

42.0 (20.0; 79.0)

56.0 (31.2; 88.0)

42.0 (22.0; 88.0)

0.03

Type of dialysis, hemodialysis N (%)

340 (93.7)

162 (91.5)

178 (95.7)

0.10

Retransplant, N (%)

46 (12.7)

24 (13.6)

22 (11.8)

0.62

PRA Class I, N (%)

   

0.01

0–29%

273 (75.2)

123 (69.5)

150 (80.6)

 

30–80%

56 (15.4)

30 (16.9)

26 (14.0)

 

 > 80%

34 (9.4)

24 (13.6)

10 (5.4)

 

PRA Class II, N (%)

   

0.03

0–29%

315 (86.8)

148 (83.6)

167 (89.8)

 

30–80%

29 (8.0)

21 (11.9)

8 (4.3)

 

 > 80%

19 (5.2)

8 (4.5)

11 (5.9)

 

Donor type, deceased, N (%)

349 (96.1)

170 (96.0)

179 (96.2)

0.92

Donor age, years

52.0 (42.0; 60.0)

53.0 (42.0; 62.0)

52.0 (42.0; 58.0)

0.003

Donor sex, male, N (%)

192 (52.9)

85 (48.0)

107 (57.5)

0.07

Donor ethnicity, N (%)

   

0.28

White

189 (52.1)

93 (52.5)

96 (51.6)

 

Pardo

139 (38.3)

64 (36.2)

75 (40.3)

 

Afro Brazilian

32 (8.8)

17 (9.6)

15 (8.1)

 

Other

3 (0.8)

3 (1.7)

–

 

Donor CMV-IgG, positive, N (%)a

290 (91.8)

143 (89.9)

147 (93.6)

0.23

KDPI (median of %)b

80.0 (49.5; 91.0)

82.5 (61.7; 91.7)

79.0 (54.0; 89.0)

0.003

Mismatches HLA ABDR

2,0 (2,0; 3,0)

2,0 (2,0; 3,0)

2,0 (1,0; 3,0)

0.30

CIT, hours

23.1 (19.4; 28.1)

24.7 (21.5; 31.2)

22.0 (18.5; 27.5)

0.001

DGF, N (%)

187 (51.5)

108 (61.0)

79 (42.5)

 < 0.001

21-day WBC count, cell/mm3

7000 (5300; 8600)

6900 (5250; 8850)

7050 (5475; 8500)

0.99

  1. ADPKD, autosomal dominant polycystic kidney disease; CIT, cold ischemia time; CKD, chronic kidney disease; DGF, delayed graft function; HLA, human leukocyte antigen; KPDI, kidney profile donor index; PCR, polymerase chain reaction; PRA, panel reactive antibodies.
  2. aMissing data = 47.
  3. bKDPI is applicable only for deceased donors.
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