Figure 1

Representative traces showing relaxant responses to 1–30 μM eicosapentaenoic acid (EPA) on porcine basilar artery tonic contractions induced by 10 nM U46619 (a), 3 μM prostaglandin (PG) F2α (b), and 80 mM KCl (c); quantified data of relaxant responses to 1–30 μM EPA on the contractions induced by 10–30 nM U46619 (d), 3–6 μM PGF2α (e), and 80 mM KCl (f). Data are presented as mean ± SEM (n = 7 (d,e) and n = 6 (f)). ●: each drug application. PPV: 100 μM papaverine.