Figure 6

Changes in Fura-2 (an intracellular Ca2+ indicator) fluorescence intensity ratio at 510 nm elicited by 340/380 nm excitation (F340/380) induced by 3 μM prostaglandin (PG) F2α in the presence of 30 μM eicosapentaenoic acid (EPA) or 0.5% ethanol (EtOH) (a); quantified data of the F340/380 peak (b) and the F340/380 integral (area under the curve, AUC) within 5 min of PGF2α application (c) in cells expressing the human prostanoid FP receptor. Changes in F340/380 are presented as means only, and quantified data are shown as mean ± SEM (each n = 10). ●: each drug application.