Figure 8 | Scientific Reports

Figure 8

From: Eicosapentaenoic acid (EPA)-induced inhibitory effects on porcine coronary and cerebral arteries involve inhibition of prostanoid TP receptors

Figure 8

Quantified data of relaxant responses to 30 μM eicosanoic acid (EA) (a,b) and 30 μM docosapentaenoic acid (DPA) (e,f) on the contractions induced by 10–30 nM U46619 for porcine basilar (a,e) and coronary (b,f) arteries. Changes in Fura-2 fluorescence intensity ratio (F340/380) induced by 10 nM U46619 (c,g) in the presence of 30 μM EA or its vehicle (0.05% dimethylformamide/0.45% EtOH) (c) or 30 μM DPA or its vehicle (0.5% EtOH) (g) in TP-293T cells; quantified data of the F340/380 peak ratio after application of U46619 (d,h). Changes in F340/380 are presented as means only (c,g), and quantified data are presented as mean ± SEM [n = 6 (a), n = 5 (b), n = 10 (c,d), n = 7 (e), n = 6 (f), and n = 10 (g,h)]. ●: each drug application. *P < 0.05, **P < 0.01 versus EtOH or vehicle (Student's t-test). PPV: papaverine; EtOH: ethanol.

Back to article page