Figure 8
From: Evidence for oligodendrocyte progenitor cell heterogeneity in the adult mouse brain
Lumican+ fibroblast-like cells are found in the brain parenchyma. (A) Expression of Lumican, a marker of the VLMC cluster overlaid on the tSNE map. (B) Representative RNAscope images of an OPC (Pdgfra+ Olig1+) and a fibroblast-like cell (Pdgfra+ Olig1−) expressing Lumican in the brain parenchyma. White dotted line indicates the nuclear outline. (C) Quantification of the percentage of Lumican+ cells in each mouse that also expressed Pdgfra, Olig1, both, or neither. N = 3 individual experiments, n = 6 biological samples (3 males and 3 females).
