Table 2 Anthelmintic effect of 2aBZ orally administered to sheep infected with H. contortus at a single dose of 120 mg/kg.

From: Novel compound shows in vivo anthelmintic activity in gerbils and sheep infected by Haemonchus contortus

Group

EPG day 0 treatment

EPG day 7th treatment

Recovered worms

% FECR

% Worm reduction

2aBZ at 120 mg/kg

4309 ± 564.7

52.5 ± 47.63*

347.5 ± 248.6*

99.13

95.45

Control (vehicle)

4316 ± 600.2

6026 ± 1604

7633 ± 1400

  
  1. The arithmetic mean EPG and worm count of sheep treated with 2aBZ were compared with untreated control. Values are presented as mean ± SEM (n = 4). EPG = egg per gram of faeces.
  2. FECR Fecal egg count reduction.
  3. *p < 0.05 significant differences were observed (Mann–Whitney U test).
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