Table 1 Demographic characteristics of the full sample and stratified by genotype group.

From: Differential association between the GLP1R gene variants and brain functional connectivity according to the severity of alcohol use

 

Full sample (n = 181)

rs6923761

rs1042044

GG (n = 116)

AA + AG (n = 65)

Statistics

CC (n = 67)

AA + AC (n = 114)

Statistics

Age, years, Mean (SEM)

40.57 (0.90)

39.97 (1.09)

42.15 (1.57)

p = 0.24

42.13 (1.58)

39.94 (1.08)

p = 0.24

Years of education, Mean (SEM)

14.95 (0.23)

14.72 (0.28)

15.35 (0.43)

p = 0.20

15.04 (0.37)

14.89 (0.30)

p = 0.76

BMI, Kg/m2, Mean (SEM)

26.72 (0.36)

26.64 (0.45)

26.85 (0.60)

p = 0.78

26.41 (0.54)

26.89 (0.48)

p = 0.52

Sex, n (%)

Male

104 (57)

67 (58)

37 (57)

p = 0.91

39 (58)

65 (57)

p = 0.87

Female

77 (43)

49 (42)

28 (43)

28 (42)

49 (43)

Smoking status, n (%)

Smoker

47 (26)

28 (24)

19 (29)

p = 0.45

17 (25)

30 (26)

p = 0.88

Non-smoker

134 (74)

88 (76)

46 (71)

50 (75)

84 (74)

AIMs score, Mean (SEM)

Europe

0.50 (0.02)

0.37 (0.03)

0.73 (0.03)

p < 0.001

0.57 (0.04)

0.46 (0.03)

p = 0.07

Africa

0.37 (0.02)

0.47 (0.03)

0.18 (0.03)

p < 0.001

031 (0.04)

0.40 (0.03)

p = 0.15

Race, n (%)

Black

76 (42)

63 (54)

13 (20)

p < 0.001

24 (35)

52 (46)

p = 0.18

White

77 (42)

31 (27)

46 (71)

36 (54)

41 (36)

Asian

10 (6)

9 (8)

1 (1)

2 (3)

8 (7)

Multiple races

9 (5)

6 (5)

3 (5)

2 (3)

7 (6)

Unknown

9 (5)

7 (6)

2 (3)

3 (5)

6 (5)

90-day TLFB, Mean (SEM)

Average drinks per day

7.91 (0.67)

8.20 (0.88)

7.42 (1.00)

p = 0.57

8.17 (1.13)

7.76 (0.83)

p = 0.77

Heavy drinking days

30.56 (2.68)

31.29 (3.32)

29.26 (4.57)

p = 0.71

31.09 (4.46)

30.25 (3.37)

p = 0.88

AUDIT group, n (%)

Low-AUDIT

85 (47)

54 (47)

31 (48)

p = 0.88

34 (51)

51 (45)

p = 0.43

High-AUDIT

96 (53)

62 (53)

34 (52)

33 (49)

63 (55)

AUDIT total score, Mean (SEM)

14.34 (0.93)

14.02 (1.14)

14.91 (1.61)

p = 0.64

14.25 (1.60)

14.39 (1.14)

p = 0.94

  1. Continuous and categorical variables are compared using independent samples t-test and chi-squared test, respectively. AIMs, Ancestry informative markers; AUDIT, Alcohol Use Disorder Identification Test; BMI, Body Mass Index; GLP-1R, Glucagon-Like Peptide-1 Receptor; TLFB, TimeLine FollowBack.
Back to article page