Table 1 Patients’ characteristics.
Variable | IIPs | AE vs. no AE | SIPs | AE vs. no AE | ||
|---|---|---|---|---|---|---|
AE (N = 32) | No AE (N = 58) | AE (N = 9) | No AE (N = 23) | |||
Age (y) | 77 (70.8–80.3) | 76 (69.5–82) | 0.671 | 72 (66–77) | 69 (62–77) | 0.442 |
Sex (Male) | 26 (81) | 48 (83) | 0.760 | 3 (33) | 7 (30) | 0.712 |
CCIS | 3 (2–5.5) | 2 (1–3.5) | 0.061 | 2 (1–3) | 3 (1–5) | 0.549 |
IP subtype | 0.798 | 0.181 | ||||
IPF | 18 (56) | 31 (53) | ||||
Non-IPF IIPs | 14 (44) | 27 (47) | ||||
CVD-IPs | 9 (100) | 19 (83) | ||||
Others | 0 (0) | 4 (17) | ||||
Biomarkers | ||||||
LDH, IU/L | 276 (233–352) | 202 (190–235) | < 0.001 | 265 (201–394) | 246 (180–289) | 0.367 |
SP-D, ng/mL | 210 (90–325) | 129 (88–263) | 0.199 | 214 (153–291) | 176 (149–212) | 0.386 |
KL-6, U/mL | 775 (341–1455) | 617 (339–882) | 0.281 | 1249 (657–2358) | 905 (553–1956) | 0.593 |
HO-1, ng/mL | 34.3 (25.3–53.0) | 15.5 (10.2–24.1) | < 0.001 | 41.8 (21.9–53.3) | 17.1 (12.1–22.0) | 0.002 |
HRCT scores | ||||||
Honeycomb | 3 (0–8) | 3 (0–6) | 0.706 | 3 (0.5–7) | 1 (0–4) | 0.210 |
GGO | 8 (7–11) | 2 (2–4) | < 0.001 | 8 (4–17) | 3 (2–5) | 0.016 |
