Figure 2
From: Positron Emission Tomography reveals age-associated hypothalamic microglial activation in women
Partial correlation plots showing sex differences in the partial correlation (controlling for BMI) between brain age and hypothalamic TSPO expression, with the hypothalamus segmented in subjects’ native space using a deep learning technique9. Top Panel: Women show a significant positive partial correlation between brain age and hypothalamic TSPO expression (r = 0.49; p = 0.03). Bottom Panel: Men show a nonsignificant negative correlation (r = − 0.25, p = 0.24). Fisher Z-comparison showed that these correlations between brain age and hypothalamic TSPO expression different significantly between women and men (p = 0.009).
