Table 5 Hematological parameters of mice treated with synthesized Bi2O3/CuO/GO nanocomposite.

From: Antibacterial and in vivo toxicological studies of Bi2O3/CuO/GO nanocomposite synthesized via cost effective methods

Parameter

Control group (Mean ± SEM)

Treatment group (Bi2O3/CuO/GO nanocomposite) (Mean ± SEM)

p value

Hematocrit (HCT)

44.50 ± 6.51

36.01 ± 5.02

0.085

Hemoglobin (HGB)

12.55 ± 0.29

11.55 ± 0.96

0.358

Lymphocytes (LYM)

4.07 ± 0.95

3.87 ± 0.91

0.884

Mean corpuscular hemoglobin (MCH)

16.20 ± 0.48

16.63 ± 0.78

0.658

Mean corpuscular hemoglobin concentration (MCHC)

28.63 ± 2.03

32.25 ± 1.29

0.183

Mean corpuscular volume (MCV)

57.06 ± 2.08

50.75 ± 0.67

0.028*

Mean platelet volume (MPV)

8.32 ± 0.20

7.02 ± 0.22

0.005**

Clotting time (CT)

0.56 ± 0.07

0.42 ± 0.19

0.511

Platelet distribution width (PDW)

14.54 ± 2.72

12.44 ± 1.99

0.557

Platelet large cell ratio (PLCR)

18.23 ± 2.88

6.86 ± 1.89

0.016*

Platelets (PLT)

673.80 ± 87.18

471.50 ± 149.40

0.286

Red blood cells (RBC)

7.75 ± 0.31

7.08 ± 0.43

0.251

White blood cells (WBC)

5.10 ± 0.70

4.22 ± 0.79

0.440

Red cell distribution width- coefficient of variation (RDW-CV)

24.00 ± 1.13

26.63 ± 1.75

0.258

Red cell distribution width—standard deviation (RDW-SD)

46.73 ± 0.60

43.59 ± 2.73

0.305

  1. The values are expressed as Mean ± SEM and statistically analyzed using t-test. The results of the treatment group are compared with those of the control group and considered non-significant if p > 0.05, significant if p < 0.05 and more significant if p < 0.0185.
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