Table 1 Characteristics of participants by disease status.

From: Microvascular changes in the macular and parafoveal areas of multiple sclerosis patients without optic neuritis

Characteristics

Control

(n = 78 patients; 136 eyes)

MS

(n = 58 patients; 100 eyes)

P value*

Age

39 ± 11

41 ± 11

0.164

Gender, male / female

28 (36%) / 50 (64%)

19 (33%) / 39 (67%)

0.703

Spherical equivalent, D

− 0.09 ± 1.74

+ 0.19 ± 1.16

0.495

Axial length, mm

23.3 ± 0.1

23.2 ± 0.1

0.912

IOP, mmHg

15.4 ± 2.5

17.3 ± 2.8

< 0.001

Visual acuity, logMAR value (Snellen)

0.01 ± 0.06 (6/6–1)

0.01 ± 0.02 (6/6–1)

0.536

Visual field mean deviation (dB)

− 2.1 ± 2.5

–

–

Signal strength of OCT scans, out of 10

8.5 ± 1.0

8.8 ± 0.9

0.015

Signal strength of OCTA scans, out of 10

9.5 ± 0.9

9.5 ± 0.9

0.920

  1. Data presented are mean (SD) or number (%), as appropriate.
  2. IOP intraocular pressure, OCT optical coherence tomography, OCTA optical coherence tomography angiography.
  3. Significant values are in bold.
  4. *P value was obtained with Kruskal–Wallis test for non-normally distributed continuous variables, independent t-test for normally distributed continuous variables, and chi-square or Fisher’s exact tests for categorical variables.
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