Table 5 The distribution of necrotic, apoptotic and living cells incubated with IC50 concentrations of B.V. loaded cross-linked chitosan coated microspheres for 24 h.

From: Formulation, characterization and cellular toxicity assessment of a novel bee-venom microsphere in prostate cancer treatment

Tested Parameters

Mean ± SD

Percent of apoptotic cells

Percent of necrotic cells

Percent of viable cells

B.V. loaded microspheres

46.40 ± 0.80

8.90 ± 0.23

44.70 ± 0.90

Control

7.30 ± 0.30

11.30 ± 0.64

81.1 ± 0.84

Probability

0.0001***

0.015*

0.0001***

  1. *P < 0.05, **P < 0.01 and ***P < 0.001 show the significance of difference between mean viability of untreated (control) and treated (experimental) cells.
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