Figure 4 | Scientific Reports

Figure 4

From: Exploration and validation of metastasis-associated genes for skin cutaneous melanoma

Figure 4

Validation of hub genes expression in primary and metastatic melanoma samples. (A–D) Box plot of hub genes mRNA expression level were obtained by UALCAN platform. *P < 0.05;**P < 0.01; ***P < 0.001. Abbreviation: NS, no significance. (EH) Immunohistochemical staining of CDK1, RFC4, FOXM1 and KIF11 in primary melanoma and metastatic melanoma tissues using the HPA database in SKCM.

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