Figure 1
Wearable adjunct ozone and topical antibiotic therapy system. (a) Ozone and antibiotic adjunct therapy can be used as an alternative treatment for skin and soft tissue infections that do not respond to traditional therapies. Ozone provides antimicrobial properties and enables antibiotic to enter cell and disrupt cell functions, such as protein production. (b)The system utilizes gaseous ozone and gas permeable and drug-eluting nanofiber mat for treating developing wounds in the following process: (i) All-in-one wound patch with drug-eluting nanofiber mesh and gas permeable membrane is applied to skin wound. (ii) NFs begin to dissolve and release the topical antibiotics. (iii) Ozone is applied to the system for full treatment duration as topical antibiotics are completely released from NFs. Ozone and antibiotics work together to eliminate infection. (iv) Once the wound has healed, the wound patch is removed from the area. Combination of ozone and antibiotic treatment can treat antibiotic resistance infections and prevent development of new infections, leading to faster healing times.
