Table 2 Univariable and multivariable logistic regression analyses for associations between plasma proteins and the presence or absence of fatigue in patients with IBD (defined as by median or by the lowest (Q1) versus highest quartile (Q4) of fatigue scores).
Protein | Univariable analysis | Multivariable analysis | ||
|---|---|---|---|---|
OR (95% CI) | P-value | aOR (95% CI)* | P-value | |
Q1 versus Q4 fatigue scores | ||||
LIF-R | 0.21 (0.07–0.63) | 0.005 | 0.29 (0.09–0.94) | 0.039 |
VEGF-A | 2.42 (1.15–5.07) | 0.020 | 2.14 (0.97–4.73) | 0.061 |
GDNF | 0.49 (0.24–0.97) | 0.041 | 0.72 (0.34–1.51) | 0.388 |
IL-20RA | 4.72 (1.02–21.9) | 0.048 | 4.24 (0.76–23.7) | 0.100 |
DNER | 0.39 (0.15–1.02) | 0.055 | 1.12 (0.38–3.33) | 0.839 |
CD5 | 2.16 (0.99–4.49) | 0.052 | 2.32 (0.99–5.45) | 0.053 |
EN-RAGE | 0.64 (0.39–1.06) | 0.084 | 0.78 (0.46–1.35) | 0.376 |