Figure 5

Construction an evaluation of the GRS. (A,B) Cvfit and fit plots of LASSO screen. (C) Forest plot of univariate Cox analysis. (D) Forest plot of multivariate Cox analysis. (E) Cutoff value (upper panel), survival status (middle panel) and expression heatmap of the four significant prognostic genes (FZD3, RP4-597N16.1, TRBV10-3 and VSIG4) (lower panel). (F) Kaplan–Meier plotter curve between the high- and low-score groups separated by the optimal cutoff value of GRS. (G–I) The expression levels of CTLA-4, PDCD1 and CD274 between the high- and low-score groups. (J) The expression levels of 22 immune cell types between the high- and low-score groups. *p < 0.05, **p < 0.01, ***p < 0.001, ns: not significant.