Figure 4

ELISA assay for anti-FMNL1serum levels in other glomerulonephritis. (A) The same ELISA modified for detection of total IgGs was utilized to test serum levels of anti-FMNL1 antibodies in patients affected by other hystologic and genetic forms of glomerulonephritis: 23 with idiopathic FSGS, 6 with genetic FSGS and12 with IgA glomerulonephritis. Anti-FMNL1 levels were statistically significant more abundant in all these groups compared with normal subjects (P < 0.0001). (B) ROC curve analysis for anti-FMNL1IgGs in comparison with normal controls.