Figure 2
From: Detection of maternal carriers of common α-thalassemia deletions from cell-free DNA
The human α-globin gene cluster and the mutations detected. The Genes track panel illustrates the α-globin locus on the tip of chromosome 16. The approximate ranges of the four deletions (red bar) detected in this study population (−−SEA, −α3.7, α4.2 and −− THAI) are shown in the “Deletions” track. The ranges of 66 bins (blue bars) within the α-globin gene cluster are shown in the “66 bins” track. The counts of fragments mapped to each bin were used as the raw data for our prediction model. −−SEA, Southeast Asian deletion; −−THAI, Thailand deletion; AF, Allele frequency. The figure was drawn using the Gviz package.
