Table 3 Analyzing factors associated with cervical cancer recurrence using Cox regression models.

From: Cervical cancer prognosis and related risk factors for patients with cervical cancer: a long-term retrospective cohort study

Variables

Unadjusted model

Adjusted model

HR

95% CI

p value

HR

95% CI

p value

Age group (years)

< 40

Ref

Ref

40–59

0.95

0.76,1.20

0.679

0.99

0.76,1.29

0.935

≥ 60

0.67

0.45,0.99

0.045

0.61

0.37,1

0.052

Parity (times)

0–2

Ref

-

-

Ref

-

-

≥ 3

0.75

0.61,0.92

0.007

0.87

0.67,1.12

0.284

Miscarriage (times)

0

Ref

Ref

1–2

1.25

0.99,1.58

0.056

1.17

0.91,1.5

0.226

≥ 3

1.61

1.22,2.13

0.001

1.65

1.23,2.22

0.001

Clinical stage

I

Ref

Ref

II

1.37

1.09,1.72

0.007

1.73

1.24,2.41

0.001

III/IV

1.59

1.15,2.19

0.005

2.04

1.32,3.16

0.001

Pathological type

Squamous cell carcinoma

Ref

Ref

Adenocarcinoma

0.98

0.63,1.53

0.945

0.88

0.52,1.48

0.620

Others

1.68

0.87,3.26

0.125

1.94

0.71,5.29

0.193

Level of differentiation

Well

Ref

Ref

Moderate

1.09

0.78,1.53

0.600

1.01

0.71,1.44

0.946

Poor/undifferentiated

1.49

0.86,2.58

0.152

1.41

0.78,2.52

0.253

Treatment plan

Surgery only

Ref

Ref

Surgery plus adjuvant therapy

2.62

1.34,5.13

0.005

1.66

0.73,3.76

0.225

Radiotherapy only

2.26

1.15,4.46

0.019

1.35

0.56,3.25

0.503

Chemotherapy plus radiotherapy

4.69

2.34,9.38

 < 0.001

1.94

0.8,4.7

0.144

Chemotherapy only

10.83

4.49,26.14

 < 0.001

3.62

1.13,11.62

0.03

Year of admission

1992–1995

Ref

Ref

1996–2000

1.82

1.13,2.92

0.013

1.9

1.14,3.18

0.014

2001–2005

3.02

1.94,4.68

 < 0.001

3.05

1.86,4.98

 < 0.001

  1. HR hazard ratio, CI confidence intervals.