Figure 5

Treatment of PC-3 subcutaneous tumour with docetaxel. (a–e) Hematoxylin and eosin-stained sections of PC-3 tumour 0, 8, 24, 48, and 72 h after dosing with docetaxel. Scale bar is 80 µm. (f) Mitoses in present in the sections of the PC-3 tumour for control and after 24 h of dosing with docetaxel (g) Cell cycle analysis of PC-3 tumours after dosing with docetaxel and the subsequent shift in cell cycle synchronization over 0, 8, 24, 48, and 72 h.