Table 3 Efficiencies of genome editing upon application of i-GONAD with 6 transfer pulses (TP:6).
From: Efficient genome editing in wild strains of mice using the i-GONAD method
Origin | Strain | Number of females | Pregnancy | Number of pups | Pups/female | MU | KI | Genome-editing efficiency |
|---|---|---|---|---|---|---|---|---|
Laboratory | B6 | 6 | 4 (66.7%) | 16 | 2.66 | 8 | 4 | 12/15 (80.0%) |
Wild | PGN2 | 27 | 2 (7.4%) | 5 | 0.19 | 2 | 0 | 2/5 (40.0%) |
BFM/2 | 15 | 5 (33.0%) | 20 | 1.33 | 6 | 2 | 8/17 (47.1%) | |
NJL | 4 | 0 | 0 | 0.00 | Â | Â | Â | |
BLG2 | 9 | 6 (66.7%) | 18 | 2.00 | 6 | 6 | 12/18 (66.7%) | |
CHD | 4 | 0 | 0 | 0.00 | Â | Â | Â | |
SWN | 10 | 0 | 0 | 0.00 | Â | Â | Â | |
KJR | 8 | 1 (12.5%) | 1 | 0.13 | 1 | Â | 1/1 (100%) | |
MSM | 15 | 1 (6.7%) | 1 | 0.07 | Â | 1 | 1/1 (100%) | |
HMI | 9 | 0 | 0 | 0.00 | Â | Â | Â |
