Figure 4

Scatterplots of sDLL1 with creatinine (A), urea (B), and GFR (C) as well as a boxplot (D) showing the concentration of sDLL1 at different KDIGO stages. CABG coronary artery bypass graft, CTRL control, GFR glomerular filtration rate, KDIGO kidney disease: improving global outcomes, MAS major abdominal surgery, sDLL1 soluble delta-like canonical Notch ligand. ROC analyses of the established renal parameters regarding the prediction of AKI (defined as Kidney Disease: Improving Global Outcomes [KDIGO] stadium ≥ 1) compared to sDLL1 revealed a comparable predictive power of sDLL1 (Fig. 5, Table 3).