Table 5 Univariable and multivariable logistic regression analyses for intratumoral necrosis.

From: Pseudoprogression and peritumoral edema due to intratumoral necrosis after Gamma knife radiosurgery for meningioma

Variables

Univariable

Multivariable

OR (95% CI)

p

OR (95% CI)

p

Sex

Female

1.000 (–)

  

Male

2.294 (0.834–6.310)

0.108

  

Age (years)

    

 < 60

1.000 (–)

  

 ≥ 60

1.460 (0.659–3.232)

0.351

  

Tumor volume, preoperative (cc)

 < 3

1.000 (–)

  

 ≥ 3

5.220 (1.695–16.073)

0.004

1.118 (0.281–4.452)

0.874

TCTI

 < 1.5

1.000 (–)

  

 ≥ 1.5

1.055 (0.455–2.449)

0.900

  

Coverage

 < 95%

1.000 (–)

  

 ≥ 95%

1.386 (0.362–5.304)

0.633

  

Selectivity

 < 70%

1.000 (–)

1.000 (–)

 ≥ 70%

2.676 (1.097–6.527)

0.030

1.011 (0.969–1.056)

0.603

Gradient index

 < 2.70

1.000 (–)

1.000 (–)

 ≥ 2.70

0.333 (0.148–0.749)

0.008

0.454 (0.188–1.094)

0.078

70% dose volume

 < 1 cc

1.000 (––)

1.000 (–)

 ≥ 1 cc

6.875 (2.881–16.406)

 < 0.001

5.892 (2.420–14.349)

 < 0.001

70% dose ratio

 < 50%

1.000 (–)

  

 ≥ 50%

0.531 (0.230–1.226)

0.138

  
  1. Significant values are in bold.
  2. TCTI tumor/cerebellar peduncle T2-weighted imaging intensity, OR odds ratio, CI confidence interval.