Table 1 The pathological grade of rectal tissue of mice

From: Novel mechanisms underlying inhibition of inflammation-induced angiogenesis by dexamethasone and gentamicin via PI3K/AKT/NF-κB/VEGF pathways in acute radiation proctitis

Pathological grade

Healthy mice

ARP mice

DXM+GM eneman

Grade 0

10

0

0

Grade 1

0

0

4

Grade 2

0

1

2

Grade 3

0

3

3

Grade 4

0

6

1

Rank sum

11.078

6.935***

4.143###

  1. Compared to healthy mice, ***P < 0.001, compared to ARP mice, ###P < 0.001, Rank-Sum test.
  2. DXM + GM enema alleviates pathological damage and decreases pathological grade of ARP mice.
  3. The rank sum test was used for the evaluation of pathological grade. The pathological grade of ARP mice was increased compared with healthy control group mice (***P < 0.001). DXM + GM enema alleviated pathological damage and reduced pathological grade of ARP mice (###P < 0.001).
Back to article page