Table 2 Univariate and multivariate binomial logistic regression analyses, describing the associations between NH resident characteristics and RBD-IgG response after 1st and 2nd vaccine dose. Significant values are in bold.

High RBD-IgG after 1st dose (> 4160 AU/mL)

Age

1.02

[1–1.05]

0.099

–

–

–

Sex (female vs male)

1.26

[0.76–2.09]

0.366

–

–

–

< 0.0001

< 0.0001

SARS-CoV-2 infection 9–12 months before vaccination

211.36

[73.0–612.1]

< 0.0001

91.11

[22.3–372.1]

< 0.0001

SARS-CoV-2 infection 3–7 months before vaccination

86.72

[36.0–209.14]

< 0.0001

11.36

[3.29–39.2]

< 0.0001

N-IgG (S/CO > 0.5)

260

[104.4–647.4]

< 0.0001

102.6

[31.6–333.5]

< 0.0001

High RBD-IgG after 2nd dose (> 4160 AU/mL)

Age

1.00

[0.98; 1.02]

0.958

–

–

–

Sex (female vs male)

1.22

[0.79; 1.88]

0.363

–

–

–

< 0.0001

0.0024

SARS-CoV-2 infection 9–12 months before vaccination

22.26

[8.54; 58.1]

< 0.0001

6.05

[2.07–17.7]

0.0010

SARS-CoV-2 infection 3–7 months before vaccination

10.24

[5.3–19.8]

< 0.0001

2.17

[0.91–5.18]

0.0823

N-IgG (S/CO > 0.5)

36.21

[15.3–85.7]

< 0.0001

16.39

[5.97–45.0]

< 0.0001