Figure 2

Simulated time-courses of components of the developed model. The X-axis indicates the time step. Y-axes show the number of cells and molecules. Hepatocytes (a), dead cells (b), quiescent and activated Kupffer cells (c), TNF-α and TGF-β (d), HSCs and myofibroblasts (e), and myofibroblast- and portal fibroblast-derived collagens (f).