Figure 4
From: Lysyl hydroxylase 2 mediated collagen post-translational modifications and functional outcomes
Typical chromatographic patterns of collagen cross-links from the acid hydrolysates of reduced collagen obtained from MC, EV, and KO clones. In MC and EV, cross-links were composed of DHLNL, HLNL, HHMD, and Pyr. However, in KO, there was a lack of DHLNL and Pyr. DHLNL dihydroxylysinonorleucine, HLNL hydroxylysinonorleucine, HHMD histidinohydroxymerodesmosine, Pyr pyridinoline, MC MC3T3-E1, EV empty vector, KO knock-out.
