Figure 5
From: Lysyl hydroxylase 2 mediated collagen post-translational modifications and functional outcomes

Ultrastructural analysis of collagen fibrils in cell cultures by transmission electron microscopy. The cross-sectional and longitudinal views of the collagen fibrils from MC, EV, and KO. KO collagen fibrils are markedly smaller in diameter. Scale bar represents 200Â nm. Diameter distribution measured from cross-sections. Three thousand fibrils in each group were measured from a single experiment and plotted. MC MC3T3-E1, EV empty vector, KO knock-out.