Figure 3 | Scientific Reports

Figure 3

From: A novel differentiated HuH-7 cell model to examine bile acid metabolism, transport and cholestatic hepatotoxicity

Figure 3The alternative text for this image may have been generated using AI.

Abundance of bile acid-relevant proteins in differentiated HuH-7 cells with overlay measured by quantitative targeted absolute proteomics (QTAP) analysis. Membrane protein abundance (pmol/mg protein; mean ± standard deviation, n = 3) of select bile acid-relevant proteins in 2-week cultured HuH-7 cells treated with 1 µM dexamethasone (DEX) and/or 0.5% DMSO was plotted as scatter plots for individual proteins. Statistically significant differences with respect to control (Ctrl) were calculated for each protein using an ordinary one-way ANOVA and Dunnett’s multiple comparison test (*, p < 0.05). N.D., not detected; LLOQ, lower limit of quantitation (0.1 pmol/mg protein).

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