Figure 2 | Scientific Reports

Figure 2

From: Loureirin B downregulates osteoclast differentiation of bone marrow macrophages by targeting the MAPK signaling pathway

Figure 2The alternative text for this image may have been generated using AI.

The score of the target protein that LrB acts on BMMs and the proportion of different score segments. (1) Targets with Score > 1000: high-affinity binding, characterized by fast binding and high affinity. Such target proteins are usually related to acute drug efficacy, acute toxicity and drug metabolism; (2) Targets with 200 < Score < 1000 Point: medium-affinity binding, characterized by binding speed and medium affinity, such targets are usually related to chronic drug effects; (3) Targets with 100 < Score < 200: low-affinity binding, characterized by slow binding and relatively low affinity Low, such targets are usually related to drug delivery, blood drug concentration maintenance, and bypass drug efficacy.

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