Figure 1 | Scientific Reports

Figure 1

From: Pinocembrin suppresses oxidized low-density lipoprotein-triggered NLRP3 inflammasome/GSDMD-mediated endothelial cell pyroptosis through an Nrf2-dependent signaling pathway

Figure 1

oxLDL stimulates cytotoxicity and pyroptosis among HUVECs. HUVECs were incubated with oxLDL (0–150 mg/L or 0–100 mg/L) for 24 h. CCK8 assay (a) and LDH assay (b) showing cell viability and LDH activity in media. (c) WB assays showing the protein levels of pyroptosis-related makers. ELISA assays for IL-1β (d) and IL-18 (e) in media. Data are described with mean ± SD of at least 3 different experiments. *P < 0.05; **P < 0.01 vs. cells in the control group.

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